TopBrainPills Rating: 80%

Doxiderol Review: Good Short-Term Energy Booster, Still Could Be Better

Cognitive enhancing supplements are typically designed to increase focus, improve memory and enhance mental energy. Even though a lot of brands promise us the same things, only some have actually dedicated time and energy into creating a successful formula that does not cause terrible side effects. After reviewing dozens of brain boosting pills, we have gained the ability to differentiate the bad from the good almost instantly. When we come across esteemed products such as Nitrovit, we get reminded why we started this entire review site in the first place. Companies with a genuine aim to help those battling with attention issues almost always include ingredients of the finest quality in their products. They do so in hope to improve symptoms of ADD/ADHD without causing addiction, trouble sleeping, headaches, etc. In these cases, customers who have struggled for years to fight their memory and focus problems acquire the help they need and their lives can change for the better. Like Nitrovit, a lot of products have managed to do this. In this review, we wonder whether Doxiderol is capable of the same thing.


Supplement Facts
Vitamin B5 2mg
Vitamin B6 5mg
Vitamin B12 6mcg
Doxiderol Proprietary Blend 251.7mg
Acetyl L-Carnitine
Bacopa Extract
Huperzine A


At first glance, we were not too impressed with Doxiderol’s decision to hide the dose of each substance under “Proprietary Blend”. Nonetheless, let’s set aside this small hiccup for a while. Their formula does contain some of our favorite nootropics such as Huperzine A and Vinpocetine. When combined, these two compounds are able to increase blood-flow to the brain, improve memory formation, and protect neural cells from deteriorating. However, a dose of 200-400mcg of Huperzine A and 15-30mg of Vinpocetine are required for any results to occur. If Doxiderol has included lower amounts, then these two compounds would be completely useless. Since we have no way of ensuring Doxiderol’s exact doses, we must depend on customer reviews to test the effectiveness of the product.

Overall Dose Potency: 16/20

We cannot confirm the potency of the Doxiderol pills because the manufacturer has not disclosed detailed information regarding doses. Most nootropics come in the form of a 650mg capsule. Even in these cases, they’re advised to be taken 2-4 times a day in order for any results to take place. Even though Doxiderol’s blend is only around 260mg in each capsule, the dose is recommended to be taken once a day. We are therefore skeptical about the overall potency with so little in each one.
The 3 B-vitamins make up just under 8mg. The Vinpocetine and Huperzine A will constitute less than 30mg total, leaving 220 odd mg to be shared between the Bacopa, ALCAR (Acetyl L-Carnitine) and DMAA – A banned amphetamine like substance so be warned if you partake in athletics or sports, or work for an employer that drug tests.
As someone who takes 1000mg of ALCAR a day (and has for pretty much 2 years now) I really can’t see how effective that would be, so it would appear we have the Dimethylamine and Vit B6 giving the energy boost (so you know it’s working!) and the Huperzine A to boost memory. The ALCAR is probably sat at around 100 – 150 mg which is too low to have any real effect in my opinion, but overall not a bad formulation… If used as a base stack with you adding perhaps a racetam or Choline source on top in a reasonable quantity.

Short Term Results: 18/20

During the first week of trial, we were surprised to see that something did shine through. Taking Doxiderol allowed our testers to have greater mental clarity and improved focus. All 5 testers also agreed that they felt a sudden surge of energy within 30 minutes of taking the product.

Long Term Results: 15/20

By the second week however, the effectiveness of the product died along with our excitement. Perhaps the users quickly developed a tolerance and therefore were desensitized to the ingredients. Another explanation could be that Doxiderol packs very low doses of each ingredient.

Side Effects: 17/20

The only major side effect that we experienced with Doxiderol was a bad crash at the end of the day. When we say “crash”, we mean a sudden drop of energy levels and a sluggish feeling. While this could be prevented, it’s not the worst side effect that a supplement could bring. Fortunately, Doxiderol did not cause any headaches, nausea, trouble sleeping or irritability.

Price/Value: 14/20

A 30-cap bottle costs $34.95 and a 90-cap bottle costs $78.64. Obviously, if you would be taking 2-3 capsules a day, due to the reduced effectiveness of their recommended dosage, you’d have to go for the latter option for a month’s supply, which is notably more expensive than the price offered by most other nootropics. However, it’s not ridiculously expensive, and we would actually say that it’s worth the quality of ingredients. With that said, we can’t help but mention that there are products with more potent doses for a cheaper price, such as our Editors’ choice Nitrovit.


Surprisingly, Doxiderol scored better than we thought it would. The only part where Doxiderol suffers from is the fact that it only has a 300mg dosage, in which the ingredients are hidden. At a price of $79 a month, it’s not incredibly expensive, although the price is still steeper than most.
I think the best way to summarize Doxiderol is to say it isn’t bad as a base stack to add other nootropics too, but overall we get the feeling that the formula was put together by business people using Wiki, as opposed to nootropic fans or neuroscientists who have made this a labor of love.

It is also worth noting the legal status of the ingredient DMAA (Dimethylamylamine) within sports: Due to its structural similarity to amphetamines, it gives a false positive in drug tested competitions for amphetamines and thus should not be used by competing athletes. (,3-dimethylamylamine/